Understanding the MTHFR Gene: Personalized Health for Fertility and Heart Health

Have you ever heard of the MTHFR gene? It plays a crucial role in your health by producing an enzyme that converts folate from your diet into its active form, folic acid. This active folic acid is vital for processes like cell division, DNA production, and protein metabolism. But did you know that variations in this gene can affect how your body handles folate, impacting both fertility and heart health?

The MTHFR Gene and Fertility

Folate is essential during pregnancy, especially for forming the neural tube, which develops into your baby’s spine and brain. Without enough folate, there’s a higher risk of neural tube defects. MTHFR comes into play here because some variations can slow down the conversion of folate to folic acid, potentially leading to deficiencies that affect fertility and pregnancy. The CDC recommends women consume 400 mcg of folic acid before and during pregnancy to reduce these risks. Foods rich in folic acid, like dark leafy greens, beans, citrus fruits, and peanuts, can help, but knowing your MTHFR status can guide you in choosing the right diet and supplements for your needs.

The MTHFR Gene and Heart Health

Your heart health is another area where MTHFR matters. If you have a variation that reduces the enzyme’s efficiency, your body might struggle to convert homocysteine to methionine, leading to elevated homocysteine levels. High homocysteine can damage artery linings, increasing the risk of blood clots and other heart conditions. Understanding your gene status can empower you to make dietary changes that lower these risks and support your heart health.

Why Genetic Testing Matters

Getting tested gives you valuable insights into how your body processes folate and homocysteine. Whether you’re planning a pregnancy or looking to protect your heart, knowing your genetic makeup allows you to make informed decisions about your diet, supplements, and overall health.

We offer genetic testing that provides detailed information about your MTHFR gene and other genes involved in nutrient metabolism. Our dietitians are here to help you understand your results and create a personalized plan to support your health goals.

Taking control of your health starts with understanding your genetics—get tested and choose what’s right for you!

References:

  • Centers for Disease Control and Prevention. (2022). General information about NTDs, folic acid, and folate. CDC
  • Watson, B. (2023). Cardiovascular disease and MTHFR gene. Xcode Life